Defined as the development of bone and soft-tissue replacement materials, by biological and biochemical means, to enhance musculoskeletal healing and mitigate common complications. This emerging branch of medical science gives healthcare providers a number of options for decreasing patients’ symptom and while substantially decreasing recovery time. It can relieve joint pain without surgery. A breakthrough method is one form of orthobiologics which can promote the body’s own musculoskeletal healing tendencies. This procedure has massive potential for alleviating symptoms associated with plantar fasciitis, knee and shoulder disorders, ligament sprains and other injuries and conditions.